AmWiner transdermal technology offers distributors an attractive alternative to oral drug delivery because they are a non-invasive route for drug administration ensuring predictable drug plasma levels and patient compliance improvement. All our products are available as transdermal patch contract manufactured in-adhesive type are pharmaceutical forms that deliver an active ingredient through the transdermal route. They consist of a support layer, an adhesive matrix containing the active ingredient and a release layer that is discarded when the product is applied to the skin.
Transdermal topical drug products + Minoxidil hair loss treatment patches + Dark eye circle and targeted facial spots + Acne skincare and even tone chemical peels + Fast wrinkle eraser and facial tightening + Suitable for all skin types of allergy free hydrogels
Our customized transdermal patch formulations range from Acne treatment, Wrinkles, Stretchmarks, Vitiligo, Scar, Rosacea, Hair loss treatment patches for targeted bald areas and patches for chemical peels. We offer topical patches in doses ranging from 10 MG up to 100 MG, with adhesives that are flexible, breathable, and removable.
AmWiner is an ISO 13485 certified contract manufacturer of hydrogels transdermal patches, pharmaceutical and cosmetic and transdermal patches with additives. We work with customers whose concepts are in all stages of development from conceptual through full production. We help customers create prototype samples, manufacture complete product lines, warehouse, and direct ship products to fulfilment centers. We work with companies to design and manufacture small and large transdermal and topical patch die cuts that meet the most stringent health and safety standards. We work with small start-up companies as well as large, well-established companies to help them get their medicinal patches onto the market.
Customized Transdermal Product Development
We offer customized medicine and product development, prototyping, and stability testing capabilities. We will help design your product to be manufacturable and cost effective and conduct extensive testing procedures for your product to guarantee efficacy and active ingredients dermal delivery and develop a new formula from scratch or change our existing liquid formula to custom hydrogel or hydrocolloid acne patch, and integrated other ingredients such as antibacterial agents, cosmetic agents, Minoxidil, menopausal aid, pain killers, active pharmaceuticals, and your choices.
How We Manufacture Medicinal Patches. The production of transdermal patches is a continuous process that consists of 3 stages that reflect how delicate and specific the production of this niche pharmaceutical form. The process consists of the following stages:
Mixing of the active ingredients + Coating, Drying and Laminating + Die-cutting and Packaging.
Mixing
It represents the beginning of the manufacturing process, and its objective is to achieve the integration of the active and non-active ingredients that make up the formulation. The first step is to fraction and weigh each of the materials that will be part of the mixture, according to what is established in the production click here methodology. At this stage it is important to control the correct dissolution and dispersion of the components to guarantee the homogeneity of the adhesive mixture necessary to ensure the correct dosage and that all the units produced are effective and safe because of the controlled release of the active ingredient.
Coating, Drying and Laminating
Once the mixture is obtained, the following process consists of three sub-stages: first is the coating, which is a continuous process where the mixture is uniformly dispensed on the release liner, then both components go through various drying stations to evaporate the volatile components of the mixture, to obtain the “adhesive mixture” Finally, both components are joined at the exit of the drying stations with the backing film, thus obtaining the multilayer system that forms the transdermal system. At this stage, it is important to control the weight of the adhesive matrix dispensed per unit area and the adhesive properties of the matrix, that way, a correct adhesion of the patch at the place of application and a correct dosage of the drug is guaranteed, and consequently the safety, efficiency, and quality of the drug.
Die-Cutting and Packaging
The next and last process is the die- cutting and packaging of the transdermal patches. In this stage, the shape of the patch itself is obtained with the surface established according to the dose. This process is carried out by die cutting the layers obtained in the previous process where several cuts are generally made, one of them being the cut for easy detachment, therefore allowing the patient to open the patch and then to apply it on the safer and more practical area of the skin. The 3 stages of transdermal patch production require specific adjustments associated with experience; this is one of the most pharmaceutical forms available in the industry. This is why, if your company are considering working on a transdermal patch development and manufacturing project, it is very important to work with a professional and experienced partner who can demonstrate sufficient knowledge to ensure the necessary quality of this production.
A private label kit for the medicinal transdermal patches and it`s topical serum and cream of any customized medicines for dermatologists are available upon request. Each patch is an extended or modified release regimen and delivers the same or customized dosage as the topical gels over a longer period. To learn more about Customized patches with your formula. Contact us [email protected] 469-428-5508 or www.rapheceutique.com.